Inhibitory Effects of Myricetin on Lipopolysaccharide-Induced Neuroinflammation
نویسندگان
چکیده
منابع مشابه
Caffeine attenuates lipopolysaccharide-induced neuroinflammation.
Caffeine is an antagonist at A1 and A2A adenosine receptors and epidemiological evidence suggests that caffeine consumption reduces the risk of Alzheimer's and Parkinson's diseases. Neuroinflammation plays a role in the etiology of these diseases and caffeine may provide protection through the modulation of inflammation. Adenosine has a known role in the propagation of inflammation and caffeine...
متن کاملInhibitory Effects of Ketamine on Lipopolysaccharide-Induced Microglial Activation
Microglia activated in response to brain injury release neurotoxic factors including nitric oxide (NO) and proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). Ketamine, an anesthetic induction agent, is generally reserved for use in patients with severe hypotension or respiratory depression. In this study, we found that ketamine (100 and 2...
متن کاملInhibitory Effects of Antimicrobial Peptides on Lipopolysaccharide-Induced Inflammation
Antimicrobial peptides (AMPs) are usually small molecule peptides, which display broad-spectrum antimicrobial activity, high efficiency, and stability. For the multiple-antibiotic-resistant strains, AMPs play a significant role in the development of novel antibiotics because of their broad-spectrum antimicrobial activities and specific antimicrobial mechanism. Besides broad-spectrum antibacteri...
متن کاملEffects of Clinacanthus nutans leaf extract on lipopolysaccharide -induced neuroinflammation in rats: A behavioral and 1H NMR-based metabolomics study
Objective: This research revealed the biochemical outcomes of metabolic dysregulation in serum associated with physiological sickness behavior following lipopolysaccharide (LPS)-induced neuroinflammation in rats, and treatment with Clinacanthus nutans (CN). Verification of 1H NMR analysis of the CN aqueous extract proved the existence of bioactive phytochemical constituents’ in extract. Materia...
متن کاملThe Effects of Lipopolysaccharide-induced Neuroinflammation on Learning and Forgetting in Juvenile Rats
Masters Candidate, Michele Barry, has successfully defended and made the required modifications to the text of the master's thesis for the M.S. during this Spring Semester 2016. THESIS COMMITTEE iv Acknowledgments I would like to express my sincere thanks to my advisor, Dr. Michael Vigorito, for his wisdom and guidance. His support has given me the opportunity to complete research in an area of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brain Sciences
سال: 2020
ISSN: 2076-3425
DOI: 10.3390/brainsci10010032